345757
Anti-Ganglioside GM₁ Rabbit pAb
liquid, Calbiochem®
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity (predicted by homology)
all
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Anti-Ganglioside GM₁, rabbit polyclonal, recognizes ganglioside GM₁. Cross-reacts slightly with asialo-GM₁. ELISA and TLC immunoblotting.
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes ganglioside GM1.
Recognizes ganglioside GM1. Cross-reacts slightly with asialo-GM1. Note: IB refers to TLC-IB.
Immunogen
Bovine
purified, bovine ganglioside GM₁
Application
ELISA (see comments)
TLC Immunoblotting (1:1000, colormetric)
TLC Immunoblotting (1:1000, colormetric)
Warning
Toxicity: Standard Handling (A)
Physical form
Undiluted serum.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Cross-reacts slightly with asialo-GM1. Does not cross-react with other carbohydrate epitopes. Product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock. This antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the optimal working dilution.
Yoshino, H., et al. 1993. J. Neurochem.61, 658.
Kusunoki, S., et al. 1987. Neurology37, 1795.
Kusunoki, S., et al. 1987. Neurology37, 1795.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Aleksandra Somogyi et al.
International journal of molecular sciences, 19(2) (2018-02-23)
Juvenile neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene. Most JNCL patients exhibit a 1.02 kb genomic deletion removing exons 7 and 8 of this gene, which results in a truncated CLN3 protein carrying an aberrant
Danny Galleguillos et al.
Journal of neuroinflammation, 19(1), 9-9 (2022-01-08)
Gangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects in the ganglioside biosynthetic pathway result in severe neurodegenerative diseases, while a partial decrease in the levels of specific gangliosides
Neha Singhal et al.
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Cell surface glycans are known to play vital roles in muscle membrane stability and muscle disease, but to date, roles for glycans in muscle regeneration have been less well understood. Here, we describe a role for complex gangliosides synthesized by
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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