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General description
Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid (APCAs). It serves as a metal chelating agent. EDTA is an anticoagulant, which prevents blood clotting by chelating calcium from the blood. EDTA-mediated platelet aggregation leads to pseudothrombocytopenia.. It is used to treat poisoning caused by heavy metals such as mercury and lead.
Application
0.5M EDTA has been used as a constituent of Dulbecco′s phosphate‐buffered saline (DPBS) for resuspension of trypsinized Human embryonic kidney 293T (HEK293T) cells in ataxin‐1 aggregation kinetics assay. It may also be used in chromatin immunoprecipitation (ChIP) assays.
Physical form
0.5M EDTA, pH 8.0.
Storage and Stability
1 year at 4°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Significance: Methods employed for preventing and eliminating biofilms are limited in their efficacy on mature biofilms. Despite this a number of antibiofilm formulations and technologies incorporating ethylenediaminetetraacetic acid (EDTA) have demonstrated efficacy on in vitro biofilms. The aim of this
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EDTA-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a spurious low platelet count due to EDTA-induced aggregation of platelets. Since the failure to recognize EDTA-dependent PTCP may result in incorrect diagnosis and inappropriate treatment, the recognition of this phenomenon is very
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