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Key Documents

LM1300

Avanti

12:0-13:0 PS

Avanti Research - A Croda Brand LM1300, methanol solution

Synonym(s):

1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phospho-L-serine (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C31H63N2O10P
CAS Number:
Molecular Weight:
654.81
UNSPSC Code:
12352211
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1300-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand LM1300

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C(O)=O)([H])N)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]

General description

Phosphatidylserine is the major anionic phospholipid in human plasma and intracellular membranes identified first in brain. It is a structural component of endoplasmic reticulum, nuclear envelopes, Golgi apparatus, inner layer of plasma membranes and outer mitochondrial membranes. PS is essential for healthy nerve cell membranes and myelin.

Application

12:0-13:0 PS has been used as a quantitative lipid standard to monitor different lipid extracts concentration.

Biochem/physiol Actions

Phosphatidylserine plays a key role in apoptosis by regulating cell signalling molecules and in monitoring membrane fluidity. Phosphatidylserine mediates the activation of enzymes and structural components.

Packaging

2 mL Amber Glass Sealed Ampule (LM1300-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics, 39, 407-427 (2010)
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
Starks MA, et al.
Journal of the International Society of Sports Nutrition, 5(1), 11-11 (2008)
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition, 31(6), 781-786 (2015)

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