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878119P

Avanti

C16 Lyso PAF

Avanti Research - A Croda Brand 878119P, powder

Synonym(s):

1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C24H52NO6P
CAS Number:
Molecular Weight:
481.65
UNSPSC Code:
12352211
NACRES:
NA.25

Pricing and availability is not currently available.

form

powder

packaging

pkg of 1 × 5 mg (878119P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 878119P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCC

InChI

1S/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1

InChI key

VLBPIWYTPAXCFJ-XMMPIXPASA-N

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This Item
878126P878101P878120P
manufacturer/tradename

Avanti Research - A Croda Brand 878119P

manufacturer/tradename

Avanti Research - A Croda Brand 878126P

manufacturer/tradename

Avanti Research - A Croda Brand 878101P

manufacturer/tradename

Avanti Research - A Croda Brand 878120P

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

form

powder

form

powder

form

powder

form

powder

lipid type

bioactive lipids
phosphoglycerides

lipid type

bioactive lipids
phosphoglycerides

lipid type

bioactive lipids
phosphoglycerides

lipid type

bioactive lipids
phosphoglycerides

Application

C16 Lyso PAF is suitable for the use in thin layer chromatography for the synthesis of acyl-platelet activating factor (PAF). It is also suitable for intraperitoneal injection into mice to compare the relative inhibitory actions of acyl-PAF, lyso-PC and lyso-PAF on alkyl PAF-induced death.[1]

Packaging

5 mL Amber Glass Screw Cap Vial (878119P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
    Michael A Kennedy et al.
    PLoS genetics, 10(1), e1004010-e1004010 (2014-01-28)
    Unbiased lipidomic approaches have identified impairments in glycerophosphocholine second messenger metabolism in patients with Alzheimer's disease. Specifically, we have shown that amyloid-β42 signals the intraneuronal accumulation of PC(O-16:0/2:0) which is associated with neurotoxicity. Similar to neuronal cells, intracellular accumulation of

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