850181P

08:0 PI

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

• Synonym(s): PI(8:0/8:0)
• Empirical Formula (Hill Notation): C₂₅H₅₀NO₁₃P
• CAS Number: 2260795-76-2
• Molecular Weight: 603.64
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850181P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

Description

General description

Phosphatidylinositol (PI), a glycerophospholipid has a head group which carries a cyclohexanol moiety. 08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) is a PI analog with a shorter acyl chain.

Application

08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) may be used:

• as a substrate for phosphatidyl-myo-inositol mannosyltransferase (PimA) to compare the effect of non-substrate phospholipids on the activity
• as a replacement for mycobacterial membranes in enzymatic assays to measure PimA activity
• as a phospholipid (PL) standard in the ion trap-time of flight (IT-TOF) system to study the fragmentation principles of unique PLs and also used as a nonendogenous PL standard for the quantitative analysis of PLs in nut samples

Biochem/physiol Actions

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol (PI) serves as a precursor of a phosphoinositides, a class of signaling lipids.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• Flash Point(F): No data available
• Flash Point(C): No data available