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640007P

Avanti

Girard Reagent

Avanti Research - A Croda Brand

Synonym(s):

1-(2-hydrazinyl-2-oxoethyl)pyridin-1-ium bromide

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About This Item

Empirical Formula (Hill Notation):
C7H10BrN3O
Molecular Weight:
232.08
UNSPSC Code:
12352116
NACRES:
NA.28

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 250 mg (640007P-250mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

Girard Reagents are N-substituted glycine hydrazides. They are classified as Girard-T (trimethylacetylhydrazide ammonium chloride), Girard-P (pyridinioacetohydrazide chloride) and Girard-D (N,N-dimethylglycine hydrazide hydrochloride). Girard hydrazones have a quaternary nitrogen moiety.

Biochem/physiol Actions

Girard reagents facilitate the isolation of carbonyl compounds from their complex mixtures, by generating water-soluble hydrazones. These reagents are sensitive and selective. Girard P reagent is used for the derivatization of oxosteroids to form the corresponding Girard hydrazones, which can be detected by tandem mass spectroscopy or electrospray (ES) mass spectrometry.

Packaging

20 mL Clear Glass Screw Cap Vial (640007P-250mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Analysis of oxysterols by electrospray tandem mass spectrometry
Griffiths WJ, et al.
Journal of the American Society For Mass Spectrometry, 17(3), 341-362 (2006)
Transition metal complexes with Girard reagents and their hydrazones
Vojinovic-Jevsic LS, et al.
J. Serb. Chem. Soc., 77(9), 1129-1155 (2012)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
Roberg-Larsen H, et al.
Journal of Lipid Research, 55(7), 1531-1536 (2014)

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