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QBD10219

Sigma-Aldrich

Biotin-dPEG®4-hydrazide

Synonym(s):

21-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-4,7,10,13-tetraoxa-16-azaheneicosanoic acid hydrazide, Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C21H39N5O7S
CAS Number:
Molecular Weight:
505.63
UNSPSC Code:
12352125
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: carbonyl reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCOCCOCCOCCOCCNC(CCCCC1SCC(C1N2)NC2=O)=O)NN

Features and Benefits

Biotin-dPEG®4-hydrazide allows biotin labeling of molecules with free aldehydes or ketones. Biotin-dPEG®4-hydrazide reacts to form a hydrazones. This reagent is highly useful for labeling carbohydrates, glycoproteins, and other molecules with biotin following oxidation of the carbohydrate or glycan with sodium periodate or by chemical installation of an aldehyde or ketone on the target molecule. The dPEG® spacer is a single molecular weight PEG that provides excellent water solubility while extending the biotin moiety away from the surface of the labeled molecule for enhanced binding to avidin or streptavidin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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