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523925

Sigma-Aldrich

Poly(acrylic acid) solution

average Mw ~100,000, 35 wt. % in H2O

Synonym(s):

PAA

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About This Item

Linear Formula:
(C3H4O2)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

mol wt

average Mw ~100,000

concentration

35 wt. % in H2O

density

1.14 g/mL at 25 °C

SMILES string

OC(=O)C=C

InChI

1S/C3H4O2.Na/c1-2-3(4)5;/h2H,1H2,(H,4,5);/q;+1/p-1

InChI key

NNMHYFLPFNGQFZ-UHFFFAOYSA-M

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General description

Poly (acrylic acid) (PAA) is hygroscopic, brittle and colorless in nature with Tg at nearly 106oC. At temperatures above 200, up to 250oC, it loses water and becomes an insoluble crosslinked polymer anhydride. Solubility of dried PAA in water increases with rise in temperature. Concentrated solutions of PAA in water are thixotropic in nature.

Application

PAA is used in the preparation of nano-hydroxyapatite polyacrylic acid (Hap/PAAc) biocomposites.†Other probable applications of PAA are: to study solute diffusion in Polyvinyl alcohol/PAA copolymer hydrogels†, synthesizing poly(N-isopropylacrylamide)-block-PAA copolymer which responds to both temperature and pH stimuli†, in preparing block copolymer of oligo (methyl methacrylate)/PAA for micellar delivery of hydrophobic drugs†, and as a thickening agent for adhesives.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

212.0 °F - closed cup

Flash Point(C)

100 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Inoue et al.
Journal of controlled release : official journal of the Controlled Release Society, 51(2-3), 221-229 (1998-08-01)
An AB block copolymer of oligo(methyl methacrylate) (oMMA) and poly(acrylic acid) (PAAc) has been synthesized. The block copolymer forms micelles in an aqueous medium, as confirmed by a fluorescence probe technique using pyrene. Doxorubicin hydrochloride was incorporated into the micelle
P L Zeeuwen et al.
The Journal of investigative dermatology, 116(5), 693-701 (2001-05-12)
Using serial analysis of gene expression on cultured human keratinocytes we found high expression levels of genes putatively involved in host protection and defense, such as proteinase inhibitors and antimicrobial proteins. One of these expressed genes was the recently discovered
Yanxia Wang et al.
International journal of pharmaceutics, 441(1-2), 170-180 (2012-12-15)
A novel galactose-decorated cross-linked micelles (cl-micelles) with ionic cores using cystamine (Cys) as a biodegradable cross-linker was prepared by using block ionomer complexes of poly(ethylene glycol)-b-poly(2-acryloxyethyl-galactose)-b-poly(acrylic acid) (PEG-b-PAEG-b-PAA) and Ca(2+) (PEG-b-PAEG-b-PAA cl-micelles/Cys). Doxorubicin (DOX) was successfully incorporated into the ionic
Daniel L Miller et al.
The Annals of thoracic surgery, 95(3), 1050-1056 (2013-01-22)
Skeletal chest wall reconstruction can be a challenge, depending on the indication, location, and health of the patient; various materials are available. Recently, biomaterials that are remodelable (bovine pericardium patch; Veritas, Synovis Life Technologies Inc, St Paul, MN) or absorbable
Lei Liu et al.
ACS nano, 7(2), 1368-1378 (2013-01-04)
Hierarchical FeOOH nanostructure array films constructed by different nanosized building blocks can be synthesized at the air-water interface via a bio-inspired gas-liquid diffusion method. In this approach, poly(acrylic acid) (PAA) as a crystal growth modifier plays a crucial role in

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