417297

Methylzinc chloride solution

2.0 M in THF

• Synonym(s): Chloromethylzinc
• Linear Formula: CH₃ZnCl
• CAS Number: 5158-46-3
• Molecular Weight: 115.88
• Beilstein: 969141
• MDL number: MFCD00192334
• UNSPSC Code: 12352103
• PubChem Substance ID: 24866136
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• concentration: 2.0 M in THF
• bp: 67 °C
• density: 1.033 g/mL at 25 °C
• SMILES string: C[Zn]Cl
• InChI: 1S/CH3.ClH.Zn/h1H3;1H;/q;;+1/p-1
• InChI key: ASUSLKVOTPUROZ-UHFFFAOYSA-M

Description

Application

Methylzinc chloride can be used in:

• Ni-catalyzed one-pot Negishi coupling with amino-heteroaryl chlorides.
• Cross-coupling with aryl fluorides in the presence of a nickel catalyst.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H314,H335,H336,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 1.4 °F - closed cup
• Flash Point(C): -17 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves