394882
N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide
>97%
Synonym(s):
MTBSTFA
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About This Item
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grade
derivatization grade
Quality Level
Assay
>97%
form
liquid
refractive index
n20/D 1.402 (lit.)
bp
172-175 °C (lit.)
density
1.036 g/mL at 25 °C (lit.)
functional group
amine
fluoro
storage temp.
2-8°C
SMILES string
CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C
InChI
1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
InChI key
QRKUHYFDBWGLHJ-UHFFFAOYSA-N
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General description
N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a highly reactive silylating reagent commonly used for silyation of carboxylic acids, alcohols, amines, and thiols. It is also used as a protection, deprotection reagent.
Application
N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) can be used:
- As a derivatizing agent in the GC-MS analysis of hydroxylated fluorenes and in the GC analysis of amino acids.
- As an efficient silylating agent for different alcohols, thiols, phenols, carboxylic acids, amines, and amides.
- To functionalize multi-walled carbon nanotubes (MWCNTs) with polar groups.
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Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
113.0 °F - closed cup
Flash Point(C)
45 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Two stage derivatization with N-(tert.-butyldimethylsilyl)-N-methyl-trifluoroacetamide (MTBSTFA) and N-methyl-bis-(trifluoroacetamide)(MBTFA) for the gas-chromatographic analysis of OH-, SH-and NH-compounds
Fresenius Journal of Analytical Chemistry, 348(5-6), 364-370 (1994)
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