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306851

Sigma-Aldrich

2-Bromo-2-methylpropionic acid

98%

Synonym(s):

α-Bromoisobutyric acid, 2-Bromo-2-methylpropionic acid

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About This Item

Linear Formula:
(CH3)2CBrCOOH
CAS Number:
2052-01-9
Molecular Weight:
167.00
Beilstein:
1745543
EC Number:
218-139-2
MDL number:
MFCD00004168
UNSPSC Code:
12352100
PubChem Substance ID:
24858541
NACRES:
NA.22

Quality Level

200

Assay

98%

bp

198-200 °C (lit.)

mp

44-47 °C (lit.)

SMILES string

CC(C)(Br)C(O)=O

InChI

1S/C4H7BrO2/c1-4(2,5)3(6)7/h1-2H3,(H,6,7)

InChI key

XXSPGBOGLXKMDU-UHFFFAOYSA-N

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General description

The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

Application

2-Bromo-2-methylpropionic acid was used in the synthesis of dextran macroinitiator for atom transfer radical polymerization (ATRP) by partial esterification of hydroxyl group of the polysaccharide.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carbohydrate polymers, 99, 728-735 (2013-11-28)
A new class of biodegradable, biomimetic and thermo-responsive dextran/synthetic glycopolymer biohybrids (dextran-graft-poly(lactobionamidoethyl methacrylate)-block-poly(di(ethylene glycol) methyl ether methacrylate), dextran-g-(PLAMA-b-PDEGMA)), was synthesized by the direct atom transfer radical polymerization (ATRP) of unprotected lactobionamidoethyl methacrylate (LAMA) glycomonomer and di(ethylene glycol) methyl ether methacrylate
Miseon Yoon et al.
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We demonstrate the successful preparation of multifunctional silica colloids by coating with 2-bromo-2-methylpropionic acid (BMPA)-stabilized quantum dots (BMPA-QDs) and BMPA-stabilized iron oxide particles (BMPA-Fe(3)O(4)), along with amine-functionalized poly(amidoamine) (PAMA) dendrimers, using layer-by-layer (LbL) assembly based on a nucleophilic substitution (NS)
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The fabrication of highly efficient nonviral gene carriers with low cytotoxicity remains a challenge in gene therapy. This paper reports a facile strategy to combine the advantages of gold nanorods (Au NRs) and polycations through surface functionalization. Different Au NR
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Macromolecular bioscience, 15(11), 1605-1615 (2015-07-03)
Two derivatives of hyaluronic acid (HA) have been synthesized by atom transfer radical polymerization (ATRP), starting from an ethylenediamino HA derivative (HA-EDA) and by using diethylaminoethyl methacrylate (DEAEMA) as a monomer for polymerization. Both samples, indicated as HA-EDA-pDEAEMA a and
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