174653

Triethyl 2-phosphonopropionate

98%

• Synonym(s): 2-(Diethoxyphosphoryl)propionic acid ethyl ester
• Linear Formula: (C₂H₅O)₂P(O)CH(CH₃)CO₂C₂H₅
• CAS Number: 3699-66-9
• Molecular Weight: 238.22
• Beilstein: 1786994
• EC Number: 223-033-4
• MDL number: MFCD00009159
• UNSPSC Code: 12352108
• PubChem Substance ID: 24850353
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.431 (lit.)
• bp: 143-144 °C/12 mmHg (lit.)
• density: 1.111 g/mL at 25 °C (lit.)
• functional group: ester; phosphonate
• SMILES string: CCOC(=O)C(C)P(=O)(OCC)OCC
• InChI: 1S/C9H19O5P/c1-5-12-9(10)8(4)15(11,13-6-2)14-7-3/h8H,5-7H2,1-4H3
• InChI key: BVSRWCMAJISCTD-UHFFFAOYSA-N

Description

Application

Reactant involved in:

• Intramolecular conjugate addition for the synthesis of floresolide B
• Chemoenzymatic one-pot synthesis of γ-butyrolactones
• Enantioselective synthesis of spiroindane di-Me acetic acid via asymmetric hydrogenation
• Stereoselective intramolecular Diels-Alder reactions
• Horner-Wadsworth-Emmons reactions

This Wittig-Horner reagent condenses with a wide variety of aldehydes and ketones to form acrylates.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 192.2 °F - closed cup
• Flash Point(C): 89 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves