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Merck

1707839

USP

伐昔洛韦 盐酸盐

United States Pharmacopeia (USP) Reference Standard

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About This Item

经验公式(希尔记法):
C13H20N6O4 · HCl
分子量:
360.80
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

valacyclovir

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2C(=O)NC(N)=Nc12

InChI

1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1

InChI 密鑰

ZCDDBUOENGJMLV-QRPNPIFTSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Valacyclovir is a prodrug of acyclovir. It is an L-valyl ester and works against herpes simplex virus type and varicella zoster virus.

應用

Valacyclovir hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Valacyclovir Compounded Oral Suspension
  • Valacyclovir Hydrochloride
  • Valacyclovir Tablets

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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UV spectrophotometric method for the estimation of valacyclovir hcl in tablet dosage form.
Ganesh, M., et al.
Journal of Chemistry, 6.3, 814-818 (2009)
Selective and rapid liquid chromatography/negative-ion electrospray ionization mass spectrometry method for the quantification of valacyclovir and its metabolite in human plasma.
Kasiari M
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 864(1-2), 78-86 (2008)
Mary J Burton et al.
The American journal of the medical sciences, 348(6), 455-459 (2014-08-28)
We performed a pilot study examining the safety and tolerability of valacyclovir in veterans with herpes simplex virus type 2 and hepatitis C virus (HCV) coinfection. We performed a randomized double-blind, placebo-controlled, crossover clinical trial in U.S. veterans with genotype
Shlomit Schaal et al.
JAMA ophthalmology, 132(7), 881-882 (2014-04-20)
Acute retinal necrosis (ARN) is an infectious retinitis primarily caused by the herpesviruses. Although the Epstein-Barr virus (EBV) has been implicated as a cause of ARN, to our knowledge, there has been no histopathologic documentation. We report the clinical history
Laurence Le Cleach et al.
The Cochrane database of systematic reviews, 8(8), CD009036-CD009036 (2014-08-05)
Genital herpes is caused by herpes simplex virus 1 (HSV-1) or 2 (HSV-2). Some infected people experience outbreaks of genital herpes, typically, characterized by vesicular and erosive localized painful genital lesions. To compare the effectiveness and safety of three oral

商品

Thin-layer chromatography method for detecting organic impurities in valacyclovir, an antiviral medication, following USP monograph guidelines.

Thin-layer chromatography method for detecting organic impurities in valacyclovir, an antiviral medication, following USP monograph guidelines.

Thin-layer chromatography method for detecting organic impurities in valacyclovir, an antiviral medication, following USP monograph guidelines.

Thin-layer chromatography method for detecting organic impurities in valacyclovir, an antiviral medication, following USP monograph guidelines.

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