1091108

辣椒素

United States Pharmacopeia (USP) Reference Standard

• 别名: 8-甲基-N-香草基-反-6-壬烯胺
• 线性分子式: (CH₃)₂CHCH=CH(CH₂)₄CONHCH₂C₆H₃-4-(OH)-3-(OCH₃)
• CAS号: 404-86-4
• 分子量: 305.41
• Beilstein: 2816484
• MDL编号: MFCD00017259
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329749225
• NACRES: NA.24

属性

• 等级: pharmaceutical primary standard
• API类: capsaicin
• 制造商/商品名称: USP
• mp: 62-65 °C (lit.)
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-8°C
• SMILES字符串: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
• InChI key: YKPUWZUDDOIDPM-SOFGYWHQSA-N
• 基因信息: human ... TRPV1(7442)

说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):

• Capsaicin
• Capsicum Oleoresin
• Capsicum
• Ginger Tincture

生化/生理作用

原型香草受体激动剂。 神经毒素；激活产生无髓C纤维的感觉神经元，其中许多含有P物质。 局部使用可使感觉神经末梢脱敏，从而产生反常的抗伤害感受作用；全身给药可对辣椒素敏感的细胞产生神经毒性，尤其是在新生动物中。辣椒的活性成分。

原型香草受体激动剂；神经毒素。辣椒的活性成分。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

安全信息

• 象形图: GHS06,GHS08,GHS05
• 警示用语：: Danger
• 危险声明: H300,H315,H317,H318,H334,H335
• 预防措施声明: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• 危险分类: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 靶器官: Respiratory system
• 储存分类代码: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 闪点(°F): 235.4 °F - closed cup
• 闪点(°C): 113 °C - closed cup