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Merck

T7576

Sigma-Aldrich

抗-TGN46 兔抗

enhanced validation

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

别名:

抗-MGC14722, 抗-TGN38同源物, 抗-TGN48, 抗-TGN51, 抗-TGOLN2, 抗-TTGN2, 抗-反式高尔基体网络整合膜蛋白2前体, 抗-反式高尔基体网络蛋白2, 抗-反式高尔基体网络蛋白TGN51

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 80-100 kDa

物種活性

human

加強驗證

recombinant expression
Learn more about Antibody Enhanced Validation

濃度

~1 mg/mL

技術

immunoprecipitation (IP): 10-20 μg using TGN46 from human HepG2 cell lysates.
indirect immunofluorescence: 5-10 μg/mL using human A549 cells
western blot (chemiluminescent): 0.25-0.5 μg/mL using extracts of human HEK-293T cells expressing recombinant human TGN46

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TGOLN2(10618)

一般說明

TGN46(反式高尔基体网络蛋白,46 kDa)是大鼠TGN38的人类同源物,是反式高尔基体网络(TGN)的固有整合膜蛋白,其可在TGN和质膜之间进行组成性循环,并通过内体返回。TGN是蛋白质分泌途径、脂质和膜运输的的主要分选细胞器。TGN46是一种高度糖基化的蛋白质,可能参与调节往返TGN的膜运输。TGN46包含信号肽、内腔结构域、跨膜结构域和胞质结构域。跨膜区域和胞质尾巴分别包含保留和回收信号,可用于TGN的定位。TGN46在细胞中广泛表达。
抗TGN46可识别人反式高尔基体网络蛋白2(TGN46)。通过免疫印迹对TGN46条带的检测可被免疫肽特异性抑制。

免疫原

对应于人TGN46的氨基酸残基426-437的合成肽,N-末端添加有半胱氨酸,并与KLH偶联。与大鼠中的相应序列相同,与人的相应序列相差2个氨基酸。

應用

兔多克隆抗TGN46抗体可用于标记反式高尔基体网络蛋白2,并可通过免疫细胞化学和免疫组化(IHC)技术(例如免疫印迹、免疫沉淀和免疫荧光)进行检测和定量。它可作为探针,对反式高尔基网络蛋白2[作为反式高尔基网络(TGN)的膜转运调节成分]的存在和作用进行确定。抗TGN46可用作TGN标记。

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途,或人类或动物任何类型的消费或使用。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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