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Merck

SRP5112

Sigma-Aldrich

p63, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP63, TP73L, p40, p51, p53CP, p73H, p73L

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥70% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

分子量

~92 kDa

NCBI登錄號

應用

cell analysis

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... TP63(8626)

一般說明

p63 is the primordial member of the p53 family that acts in a conserved process of monitoring the integrity of the female germline, whereas the functions of p53 are restricted to vertebrate somatic cells for tumor suppression. p63 protein plays an important role in the development and maintenance of stratified epithelial tissues. p63 is critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis. Mutations in p63 are associated with ectodermal dysplasia, cleft lip/palate syndrome 3 (EEC3) and split-hand/foot malformation 4 (SHFM4).

外觀

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

準備報告

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Eun-Kyung Suh et al.
Nature, 444(7119), 624-628 (2006-11-24)
Meiosis in the female germ line of mammals is distinguished by a prolonged arrest in prophase of meiosis I between homologous chromosome recombination and ovulation. How DNA damage is detected in these arrested oocytes is poorly understood, but it is
A Yang et al.
Nature, 398(6729), 714-718 (1999-05-05)
The p63 gene, a homologue of the tumour-suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. Here we report that mice homozygous for a disrupted p63 gene have major defects in their limb, craniofacial

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