推荐产品
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
OC1=CC=C(C=C1NC(C2=CC=CC(S(N3CCCCC3)(=O)=O)=C2)=O)Cl
生化／生理作用
BDT001 is a selective negative allosteric modulator of Flt-3 receptor tyrosine kinase. It showed minimal binding to 25 diverse RTKs and 49 intracellular kinases. In primary cultures of adult DRG neurons, BDT001 reversed the potentiation of capsaicin-induced TRPV1 activation by FL, with a maximal effect at 1 μM. In a mouse study BDT001 alleviated nerve injury-induced peripheral neuropathic pain but had no effect on nociception in non-injured animals.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Cyril Rivat et al.
Nature communications, 9(1), 1042-1042 (2018-03-14)
Peripheral neuropathic pain (PNP) is a debilitating and intractable chronic disease, for which sensitization of somatosensory neurons present in dorsal root ganglia that project to the dorsal spinal cord is a key physiopathological process. Here, we show that hematopoietic cells
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门