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化驗
≥96% (HPLC)
形狀
powder
儲存條件
protect from light
顏色
white to beige
溶解度
H2O: 10 mg/mL, clear
儲存溫度
2-8°C
InChI
1S/C26H28ClNO.ClH/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;/h5-18H,3-4,19-20H2,1-2H3;1H/b26-25+;
InChI 密鑰
KKBZGZWPJGOGJF-BTKVJIOYSA-N
生化／生理作用
顺式克罗米酚是一种非甾体雌激素受体拮抗剂，可促进睾丸分泌促性腺激素依赖性睾酮。顺式克罗米酚是克罗米芬的反式异构体，约为反式（顺式克罗米酚）和顺式（逆式克罗米酚）的 60-40 混合物。顺式克罗米酚（反式克罗米酚）是一种雌激素拮抗剂，而逆式克罗米酚（顺式克罗米酚）是一种混合激动剂，具有雌激素活性，因此常见的副作用有时见于男性。顺式克罗米酚异构体负责抗雌激素活性和下丘脑-垂体-性腺轴的恢复。在最近的临床试验中，顺式克罗米酚使继发性性腺机能减退男性的血清 LH 和 FSH 升高，同时睾酮升高。顺式克罗米酚表现出总体上优于睾酮凝胶的效果，睾酮凝胶可升高血清睾酮，但同时可降低 LH 和 FSH。
其他說明
光敏感
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Fertility and sterility, 100(2), 341-348 (2013-07-03)
This committee opinion describes the use of clomiphene citrate, including indications, use, monitoring, and side effects. There is also a discussion of adjuvants and alternatives to clomiphene citrate therapy.
Marleen J Nahuis et al.
BMC women's health, 13, 42-42 (2013-10-29)
Clomiphene citrate (CC) is first line treatment in women with World Health Organization (WHO) type II anovulation and polycystic ovary syndrome (PCOS). Whereas 60% to 85% of these women will ovulate on CC, only about one half will have conceived
Albert Asante et al.
Fertility and sterility, 100(6), 1610-1614 (2013-10-01)
To determine whether there is a correlation between preovulatory endometrial stripe thickness (EST) and pregnancy rates in clomiphene citrate (CC)/IUI cycles. Retrospective cohort. Infertility clinic of an academic medical center. A total of 262 patients completed 562 transvaginal ultrasound-monitored CC/IUI
Feng-Qin He et al.
Dong wu xue yan jiu = Zoological research, 34(5), 487-492 (2013-10-12)
Perinatal period and adolescence are critical for brain development, which is the biological basis of an individual's sexual orientation and sexual behavior. In this study, animals were divided into two groups and their sexual orientations were observed: one group experienced
A Ayaz et al.
Journal of medicine and life, 6(2), 199-201 (2013-08-02)
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women and is associated with the reproductive and metabolic disorders. To compare the ovulation and conception rates after the treatment with Clomiphene Citrate (CC) alone and in combination with metformin
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