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Merck

SML0512

Sigma-Aldrich

BLT-4

≥98% (HPLC)

别名:

INF 271, MIT 9952-29, N-(2-Methoxyphenyl)-N′-2-naphthalenyl-urea

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About This Item

经验公式(希尔记法):
C18H16N2O2
分子量:
292.33
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 15 mg/mL (clear solution)

储存温度

room temp

SMILES字符串

COc1ccccc1NC(=O)Nc2ccc3ccccc3c2

InChI

1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)

InChI key

ISADADAHPHHLEM-UHFFFAOYSA-N

相关类别

生化/生理作用

BLT-4 is a SR-BI (Scavenger receptor, class B, type I) inhibitor.
BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.

象形图

Environment

警示用语:

Warning

危险声明

预防措施声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Thomas J F Nieland et al.
Journal of lipid research, 45(7), 1256-1265 (2004-04-23)
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a receptor that binds HDL with high affinity and mediates both the selective lipid uptake of
Elsa Westerlund et al.
Frontiers in immunology, 10, 1385-1385 (2019-07-06)
The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of
Guillemette Maurin et al.
AIDS (London, England), 29(9), 1025-1033 (2015-07-01)
Chronic hepatitis C virus (HCV) infection causes severe liver disease in HIV-infected patients and liver transplant recipients. The impact of serum and immunoglobulin on viral entry was analysed in these patients. Sera from 60 anti-HCV positive patients, including 30 who

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