推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 15 mg/mL (clear solution)
储存温度
room temp
SMILES字符串
COc1ccccc1NC(=O)Nc2ccc3ccccc3c2
InChI
1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)
InChI key
ISADADAHPHHLEM-UHFFFAOYSA-N
生化/生理作用
BLT-4 is a SR-BI (Scavenger receptor, class B, type I) inhibitor.
BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.
警示用语:
Warning
危险声明
预防措施声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Thomas J F Nieland et al.
Journal of lipid research, 45(7), 1256-1265 (2004-04-23)
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a receptor that binds HDL with high affinity and mediates both the selective lipid uptake of
Elsa Westerlund et al.
Frontiers in immunology, 10, 1385-1385 (2019-07-06)
The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of
Low cross-neutralization of hepatitis C correlates with liver disease in immunocompromized patients.
Guillemette Maurin et al.
AIDS (London, England), 29(9), 1025-1033 (2015-07-01)
Chronic hepatitis C virus (HCV) infection causes severe liver disease in HIV-infected patients and liver transplant recipients. The impact of serum and immunoglobulin on viral entry was analysed in these patients. Sera from 60 anti-HCV positive patients, including 30 who
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