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Merck
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主要文件

SML0189

Sigma-Aldrich

Indinavir sulfate salt hydrate

≥98% (HPLC), powder, antiretroviral agent

别名:

2,3,5-Trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate hydrate, Crixivan hydrate, L-735,524 hydrate, MK-639 hydrate

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About This Item

经验公式（希尔记法）:
C36H47N5O4·H2SO4 · xH2O
分子量:
711.87 (anhydrous basis)
UNSPSC代码:
51111800
NACRES:
NA.77

产品名称

Indinavir sulfate salt hydrate, ≥98% (HPLC)

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to tan

溶解性

H2O: ≥15 mg/mL

创始人

Merck & Co., Inc., Kenilworth, NJ, U.S.

储存温度

2-8°C

应用

Indinavir sulfate salt hydrate may be used in HIV-related cell signaling studies.

生化/生理作用

Indinavir sulfate is an antiretroviral; HIV Protease Inhibitor
Indinavir sulfate is an antiviral HIV protease inhibitor.
Indinavir sulfate suppresses the replication of HIV and is an important component of antiretroviral therapy for initial treatment of HIV infection. It is known to cause renal and urologic toxicity.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000174916
0000174916
0000117009
0000117008
0000115843

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Ryan D Cooper et al.
Nephron. Clinical practice, 118(3), c262-c268 (2011-01-08)
The introduction of potent combination antiretroviral therapy (ART) in the treatment of HIV infection has permitted reliable control of disease progression and has markedly improved survival among people with HIV. As a result, health care providers and patients have shifted
Benjamin Seyer et al.
Journal of neurochemistry, 153(4), 485-494 (2019-09-27)
Ethyl2-acetylamino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylate (HFI-419), the benzopyran-based inhibitor of insulin-regulated aminopeptidase (IRAP), has previously been shown to improve spatial working and recognition memory in rodents. However, the mechanism of its cognitive-enhancing effect remains unknown. There is a close correlation between dendritic spine density

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Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

Bioactive Molecules for Immunology Research

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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