SML0148

Imidapril hydrochloride

≥98% (HPLC)

• 别名: (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride, Novaloc, TA 6366, Tanapril
• 经验公式（希尔记法）: C₂₀H₂₇N₃O₆ · HCl
• CAS号: 89396-94-1
• 分子量: 441.91
• MDL编号: MFCD00923828
• UNSPSC代码: 12352200
• PubChem化学物质编号: 329825196
• NACRES: NA.77

属性

• 方案: ≥98% (HPLC)
• 表单: powder
• 旋光性: [α]/D -50 to -70° in ethanol (c=0.5)
• 颜色: white to tan
• 溶解性: H₂O: ≥5 mg/mL
• 创始人: Trinity Pharma Solutions
• 储存温度: −20°C
• SMILES字符串: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2[C@@H](CN(C)C2=O)C(O)=O
• InChI: 1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
• InChI key: LSLQGMMMRMDXHN-GEUPQXMHSA-N

说明

一般描述

Imidapril comprises large acyl moiety and is hydrolyzed by carboxylesterase (CES) 1.

应用

Imidapril hydrochloride may be used to test its effect on pharyngeal and laryngeal muscle to treat impaired swallowing.

Imidapril hydrochloride was used as a standard in bioequivalence test by LC/MS method.

生化/生理作用

Angiotensin Converting Enzyme (ACE) inhibitor

Imidapril hydrochloride is a long-acting inhibitor of angiotensin converting enzyme used in the treatment of hypertension, congestive heart failure and diabetic nephropathy. It restores decreased airway sensation and bladder sensation in patients with multiple sclerosis.

Imidapril is a potent angiotensin converting enzyme inhibitor and anti-hypertensive.

特点和优势

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Trinity Pharma Solutions. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable