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化驗
≥95% (HPLC)
形狀
lyophilized
成份
Peptide Content, ≥85%
儲存條件
protect from light
儲存溫度
−20°C
Amino Acid Sequence
Z-Ile-Glu-Thr-Asp-pNA
應用
Caspase 8 Processing Enzyme Substrate (Z-Ile-Glu-Thr-Asp-pNA; zIETD-pNa) is used as a substrate to identify, differentiate and characterize Granzyme B, Caspase 3 Processing Enzyme(s) and Caspase 8 Processing enzyme(s). Z-Ile-Glu-Thr-Asp-pNA is closely related to Z-Ile-Glu-Thr-Asp-fluoromethylketone (zIETD-fmk), an inhibitor of Caspase 8.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Journal of leukocyte biology, 75(6), 1045-1055 (2004-04-13)
Caspases are key molecules in the control of apoptosis, but relatively little is known about their contribution to eosinophil apoptosis. We examined caspase-3, -8, and -9 activities in receptor ligation-dependent apoptosis induction in the differentiated human eosinophilic cell line EoL-1.
The Journal of biological chemistry, 279(35), 37201-37207 (2004-06-19)
Mast cells play an important role in both allergy and innate immunity. Recently, we demonstrated an active interaction between human mast cells and Pseudomonas aeruginosa leading to the production of multiple cytokines. Here, we show that both primary cultured human
Journal of immunology (Baltimore, Md. : 1950), 165(10), 5612-5620 (2000-11-09)
Past studies have shown that TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis in a high proportion of cultured melanoma by caspase-dependent mechanisms. In the present studies we have examined whether TRAIL-induced apoptosis of melanoma was mediated by direct activation of effector
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