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Merck
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Key Documents

SAB5702298

Sigma-Aldrich

Anti-nNOS Antibody, clone 5K9R2, Rabbit Monoclonal

别名:

NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS, nitric oxide synthase 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

5K9R2, monoclonal

形狀

liquid

分子量

160 kDa

物種活性

rat, rat, human

濃度

3 mg/mL

技術

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

QLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... nNOS (4842)

一般說明

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5′ UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1335-1434 of human nNOS (P29475).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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