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Merck
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主要文件

SAB5702019

Sigma-Aldrich

Anti-β-arrestin1 Antibody, clone F7C2, Rabbit Monoclonal

别名:

ARRB1,ARB1,ARR1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

物料

colorless

克隆

F7C2, monoclonal

表单

liquid

分子量

51 kDa

种属反应性

mouse, mouse

浓度

1.00 mg/mL

技术

western blot: 1:500 - 1:2000

颜色

colorless

同位素/亚型

IgG

免疫原序列

MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRL

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ARRB1(408)

一般描述

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human β-arrestin1 (P49407).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB

储存分类代码

10 - Combustible liquids

WGK

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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