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Merck
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Key Documents

SAB5701700

Sigma-Aldrich

Anti-Fascin/FSCN1 antibody produced in rabbit

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

生物源

rabbit

品質等級

抗體產品種類

primary antibodies

無性繁殖

monoclonal

形狀

liquid

物種活性

rat, mouse, human

濃度

0.28 mg/mL

技術

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... FSCN1(6624)

一般說明

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

免疫原

A synthesized peptide derived from human Fascin/FSCN1

外觀

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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