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Merck
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主要文件

SAB5500007

Sigma-Aldrich

Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal

clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody

别名:

Anti-AIS, Anti-AR8, Anti-DHTR, Anti-HUMARA, Anti-HYSP1, Anti-KD, Anti-NR3C4, Anti-SBMA, Anti-SMAX1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
IHC
無性繁殖:
SP242, monoclonal
物種活性:
human (tested)
citations:
2
技術:
immunohistochemistry: 1:100

生物源

rabbit

品質等級

重組細胞

expressed in proprietary host

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

SP242, monoclonal

物種活性

human (tested)

物種活性(以同源性預測)

dog, pig, rat, rabbit, mouse

技術

immunohistochemistry: 1:100

同型

IgG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... AR(367)

一般說明

Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer.

免疫原

Synthetic peptide from the C-terminus of human androgen receptor protein.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Racial Differences in Androgen Receptor (AR) and AR Splice Variants (AR-SVs) Expression in Treatment-Na??ve Androgen-Dependent Prostate Cancer.
Khan, et al.
Biomedicines, 11 (2023)
Pei Zhao et al.
Asian journal of urology, 6(1), 109-113 (2019-02-19)
Small cell prostate carcinoma (SCPC) is a rare and highly malignant subtype of prostate cancer. SCPC frequently lacks androgen receptor (AR) and prostate-specific antigen (PSA) expression, and often responds poorly to androgen deprivation therapy (ADT). AR splice variant-7 (AR-V7) is

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