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Merck
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主要文件

SAB4501790

Sigma-Aldrich

Anti-LY6E antibody produced in rabbit

affinity isolated antibody

别名:

Ly-6E, Lymphocyte antigen 6E, RIG-E, Retinoic acid-induced gene E protein, Thymic shared antigen 1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 13 kDa

种属反应性

human

浓度

~1 mg/mL

技术

ELISA: 1:20000
immunofluorescence: 1:100-1:500

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... LY6E(4061)

一般描述

Anti-LY6E Antibody detects endogenous levels of total LY6E protein.
Anti-LY6E Antibody detects endogenous levels of total LY6E protein. LY6E (lymphocyte antigen 6 family member E) is a glycosylphosphatidylinositol-anchored, interferon (IFN)-inducible protein, that is located on human chromosome 8q24. It is also called as RIG-E.

免疫原

The antiserum was produced against synthesized peptide derived from human LY6E.

Immunogen Range: 17-66

生化/生理作用

LY6E (lymphocyte antigen 6 family member E) controls T lymphocytes proliferation, differentiation and development. It induces HIV-1 Infection. Overexpression of LY6E gene in the peripheral blood cells of individuals with SLE (systemic lupus erythematosus) is associated with lupus activity.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Interferon-inducible LY6E Protein Promotes HIV-1 Infection.
Yu J, et al.
Journal of Biochemistry, 292(11), 4674-4685 (2017)
RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.
M Mao, et al.
Proceedings of the National Academy of Sciences of the USA, 93(12), 5910-5914 (1996)
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.
J Tang, et al.
Lupus, 17(9), 805-813 (2008)

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