推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 44 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... ADORA2A(135)
一般說明
Anti-ADORA2A Antibody detects endogenous levels of total ADORA2A protein.
Adenosine A2a receptor (ADORA2A) is a G protein-coupled receptor. It is highly expressed in the brain. It is located on human chromosome 22q11.23.
免疫原
The antiserum was produced against synthesized peptide derived from human ADORA2A.
Immunogen Range: 321-370
Immunogen Range: 321-370
生化/生理作用
Activation of the adenosine A2a receptor (ADORA2A) prevents T-cell proliferation and production of pro-inflammatory cytokines. It functions in increasing cytosolic cAMP levels. The protein has been associated with stimulation of liver ischemic preconditioning. ADORA2A is also linked to dermal fibrosis and scleroderma.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Pharmacological Preconditioning by Adenosine A2a Receptor Stimulation: Features of the Protected Liver Cell Phenotype
BioMed Research International (2015)
Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance
Purinergic Signaling, 9(4), 573-583 (2013)
A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease
Neurobiology of Disease, 35(3), 474-476 (2009)
[Adenosine A2A receptor as a drug target for treatment of sepsis]
Molekuliarnaia Biologiia, 50(2), 231-245 (2016)
Adenosine A(2A) receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder.
European Child & Adolescent Psychiatry, 19(1), 67-74 (2010)
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