SAB4300366

Anti-TP53 (Ab-33) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-FLJ92943 antibody produced in rabbit, Anti-LFS1 antibody produced in rabbit, Anti-TRP53 antibody produced in rabbit, Anti-p53 antibody produced in rabbit, Anti-tumor protein p53 antibody produced in rabbit
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~53 kDa
• 物種活性: human
• 濃度: 1 mg/mL
• 技術: western blot: 1:500-1:1000
• 同型: IgG
• 免疫原序列: (V-L-S-P-L)
• NCBI登錄號: NP_000537.3
• UniProt登錄號: P04637
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TP53(7157)

说明

免疫原

Peptide sequence around aa. 31-35 (V-L-S-P-L), according to the protein TP53.

特點和優勢

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標靶描述

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable