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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
29 kDa
种属反应性
bovine, rat, dog, mouse, human
浓度
0.5-1 mg/mL
技术
immunoblotting: suitable
immunohistochemistry: suitable
登记号
NM_002592
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PCNA(5111)
一般描述
增殖细胞核抗原(PCNA)是一种核蛋白，在哺乳动物中广泛表达。它是一种环状同型三聚体蛋白，在胸腺、骨髓、胎肝以及少数小肠和结肠细胞中高水平表达。PCNA主要位于细胞核。PCNA基因是单拷贝基因，定位于人类染色体20p13。
免疫原
靶向人IGFBP7 C末端区域的合成肽
应用
抗PCNA抗体已用于：
- 免疫印迹(1:500) (1:1,000) (1:750)
- far-western蛋白相互作用分析(1:1000)
- 免疫组化(1?:?50) (1:1000)
- 增殖细胞核抗原(PCNA)overlay assay（蛋白铺覆检测）(1:1,000)
生化/生理作用
增殖细胞核抗原(PCNA)参与DNA复制和修复。它是一种聚合酶δ辅助因子。在冈崎片段成熟中起着重要作用。PCNA可作为慢性淋巴细胞白血病(CLL)的预后和诊断标志物。在乳腺和十二指肠癌中PCNA蛋白也有高表达。
序列
合成肽位于以下区域内： LNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
外形
本品为溶于1x PBS缓冲液的纯化抗体，含 0.09% (w/v) 叠氮化钠和2%蔗糖。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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