推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
IgG fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
97402 Da
物種活性
mouse
技術
western blot: 1:1000
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
mouse ... Nlrp6(101613)
一般說明
NLR家族含pyri结构域蛋白6（NLRP6）可能是炎症小体的一部分。它属于NOD样受体家族，在肠上皮细胞中表达。
生化／生理作用
NLR家族含pyri结构域蛋白6（NLRP6）在先天免疫中起作用。它也通过调节自噬和粘液分泌维持肠道稳态。已有研究证明NLRP6缺失可阻碍大鼠中白细胞介素-18（IL-18）的产生，并增进大鼠上皮诱导损伤的易感性。
外觀
纯化多克隆抗体以PBS为溶剂，含有0.09% (W/V) 叠氮化钠。该抗体通过蛋白A柱以及随后的肽亲和纯化进行纯化。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury.
Seregin SS
Mucosal Immunology (2017)
NLRP6 Protects Il10-/- Mice from Colitis by Limiting Colonization of Akkermansia muciniphila.
Seregin SS
Cellular Reprogramming (2017)
Pierre-Gregoire Coulon et al.
Frontiers in immunology, 10, 1631-1631 (2019-08-02)
The crosstalk between the host's inflammasome system and the invading virulent/less-virulent viruses determines the outcome of the ensuing inflammatory response. An appropriate activation of inflammasomes triggers antiviral inflammatory responses that clear the virus and heal the inflamed tissue. However, an
Qifeng Deng et al.
Redox biology, 49, 102217-102217 (2021-12-24)
Maintaining host iron homeostasis is an essential component of nutritional immunity responsible for sequestrating iron from pathogens and controlling infection. Nucleotide-oligomerization domain-like receptors (NLRs) contribute to cytoplasmic sensing and antimicrobial response orchestration. However, it remains unknown whether and how NLRs
Lanqing Sun et al.
Heliyon, 10(8), e28432-e28432 (2024-04-17)
Non-typhoidal Salmonella infection is among the most frequent foodborne diseases threatening human health worldwide. The host circadian clock orchestrates daily rhythms to adapt to environmental changes, including coordinating immune function in response to potential infections. However, the molecular mechanisms underlying
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