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Merck

S6256

Sigma-Aldrich

磺胺二甲基嘧啶

99.0-101.0% (on dried basis)

别名:

4,6-二甲基磺胺嘧啶, 4-氨基-N-(4,6-二甲基-2-嘧啶基)苯磺酰胺, 磺胺二甲嘧啶

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About This Item

经验公式(希尔记法):
C12H14N4O2S
CAS号:
分子量:
278.33
Beilstein:
261304
EC號碼:
MDL號碼:
分類程式碼代碼:
51284910
PubChem物質ID:
NACRES:
NA.85

品質等級

化驗

99.0-101.0% (on dried basis)

形狀

powder or crystals

儲存條件

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

顏色

white to off-white

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

DNA synthesis | interferes
enzyme | inhibits

儲存溫度

2-8°C

SMILES 字串

Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI 密鑰

ASWVTGNCAZCNNR-UHFFFAOYSA-N

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一般說明

化学结构式:磺酰胺

應用

磺胺二甲嘧啶是一种抗生素,用于治疗支气管炎、前列腺炎和尿路感染。用于处置和消除动力学研究。其用于开发液体(如牛奶、蜂蜜和猪尿)中的定量检测技术

生化/生理作用

磺胺二甲嘧啶是一种抗微生物性硫药,通过抑制二氢喋呤合成酶而阻断二氢叶酸的合成。磺胺二甲嘧啶是细菌合成叶酸所需的对氨基苯甲酸 (PABA) 的竞争性抑制剂。诱导 CYP3A4 表达并被 N-乙酰转移酶乙酰化。它表现出性别依赖性药代动力学,由男性特有的 CYP2C11 亚型代谢。磺胺二甲嘧啶具有抑菌作用。
一种抗微生物的硫磺药物。诱导 CYP3A4 表达并被 N-乙酰转移酶乙酰化。表现出性别依赖性药代动力学,由男性特有的 CYP2C11 亚型代谢。

包裝

25G,100G

其他說明

将容器密闭保存在干燥和通风良好的地方。在干燥处保存。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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