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Merck
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PZ0343

Sigma-Aldrich

PF-06260414

≥98% (HPLC)

别名:

6-[(4R)-tetrahydro-4-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-2-yl]-1-isoquinolinecarbonitrile

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About This Item

经验公式（希尔记法）:
C14H14N4O2S
CAS号:
1612755-71-1
分子量:
302.35
分類程式碼代碼:
12352200
PubChem物質ID:
329823852
NACRES:
NA.77

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

顏色

light orange to dark orange

溶解度

DMSO: 5 mg/mL, clear (warmed)

儲存溫度

room temp

SMILES 字串

C[C@H](CNS1(=O)=O)CN1C2=CC3=CC=NC(C#N)=C3C=C2

InChI

1S/C14H14N4O2S/c1-10-8-17-21(19,20)18(9-10)12-2-3-13-11(6-12)4-5-16-14(13)7-15/h2-6,10,17H,8-9H2,1H3/t10-/m1/s1

InChI 密鑰

ZKAVFOXYJCREBQ-SNVBAGLBSA-N

生化／生理作用

PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000309563
086M4716V

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Emiliano Ventura et al.
Journal of chromatography. A, 1600, 183-196 (2019-05-06)
A semi-quantitative method was developed to monitor the misuse of 15 SARM compounds belonging to nine different families, in urine matrices from a range of species (equine, canine, human, bovine and murine). SARM residues were extracted from urine (200 μL) with

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