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Merck

P4157

Sigma-Aldrich

苯丙氨酸-精氨酸 β-萘胺 二盐酸盐

cathepsin substrate, fluorogenic, ≥98% (TLC), powder

别名:

PAβN

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About This Item

经验公式(希尔记法):
C25H30N6O2 · 2HCl
分子量:
519.47
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

苯丙氨酸-精氨酸 β-萘胺 二盐酸盐, cathepsin substrate

化驗

≥98% (TLC)

形狀

powder

溶解度

water: 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

−20°C

SMILES 字串

Cl.NC(Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc3ccccc3c2

InChI

1S/C25H30N6O2.ClH/c26-21(15-17-7-2-1-3-8-17)23(32)31-22(11-6-14-29-25(27)28)24(33)30-20-13-12-18-9-4-5-10-19(18)16-20;/h1-5,7-10,12-13,16,21-22H,6,11,14-15,26H2,(H,30,33)(H,31,32)(H4,27,28,29);1H

InChI 密鑰

ZMTAZQYLEGNUTJ-UHFFFAOYSA-N

一般說明

Phe-Arg β-萘酰胺,一种拟肽化合物, 是一种外排泵抑制剂(EPI)。它可作用于革兰氏阴性细菌的主要多药耐药性外向转运蛋白。Phe-Arg-萘酰胺可在铜绿假单胞菌中降低氟喹诺酮类药物的耐药性。

應用

Phe-Arg-萘酰胺二盐酸盐用于评估外排泵对抗菌素耐药性的贡献。在存在外排泵抑制剂的条件下,它还用于最小抑菌浓度测试。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

基底

二肽基氨肽酶I(组织蛋白酶C)的底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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