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Merck

N7132

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸 锂盐 来源于酿酒酵母

≥95%

别名:

DPN, NAD, β-DPN, β-NAD, 二磷酸吡啶核苷酸, 辅酶, 辅酶 1, 辅酶Ⅰ

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About This Item

线性分子式:
C21H27N7O14P2Li
CAS号:
分子量:
670.37
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

化驗

≥95%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Li].NC(=O)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O

InChI

1S/C21H28N7O14P2.Li.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;

InChI 密鑰

CUAVZMNXWOTNRC-UHFFFAOYSA-N

基因資訊

應用

β-烟酰胺腺嘌呤二核苷酸 (NAD +) 和 β-还原型烟酰胺腺嘌呤二核苷酸 (NADH) 包括参与广泛的酶催化氧化还原反应的辅酶氧化还原对 (NAD +:NADH)。除了它的氧化还原功能外,NAD +/NADH 是ADP-核糖基转移酶(ADP-核糖基转移酶;多(ADP-核糖)聚合酶)反应中的ADP-核糖单元的供体和环状ADP-核糖(ADP-核糖基环化酶)的前体。

生化/生理作用

电子受体

其他說明

本品是普通型 NAD。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Richard P Ebstein et al.
FEBS letters, 585(11), 1529-1536 (2011-05-12)
Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
Michael O Hottiger
FEBS letters, 585(11), 1595-1599 (2011-03-23)
ADP-ribosylation is a covalent post-translational protein modification catalyzed by ADP-ribosyltransferases and is involved in important processes such as cell cycle regulation, DNA damage response, replication or transcription. Histones are ADP-ribosylated by ADP-ribosyltransferase diphtheria toxin-like 1 at specific amino acid residues
Junxiang Yin et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(11), 1783-1789 (2015-06-11)
Stroke is one of the leading causes of death. Growing evidence indicates that ketone bodies have beneficial effects in treating stroke, but their underlying mechanism remains unclear. Our previous study showed ketone bodies reduced reactive oxygen species by using NADH
Lei Wang et al.
Veterinary microbiology, 177(1-2), 175-183 (2015-03-31)
Actinobacillus pleuropneumoniae is a causative agent of porcine pleuropneumonia, which is a highly contagious endemic disease of pigs. Adhesion is a critical first step in the infection process. Trimeric autotransporter adhesions (TAAs) have been identified as novel virulence factors; however
Joan J Soldevila-Barreda et al.
Nature communications, 6, 6582-6582 (2015-03-21)
Organometallic complexes are effective hydrogenation catalysts for organic reactions. For example, Noyori-type ruthenium complexes catalyse reduction of ketones by transfer of hydride from formate. Here we show that such catalytic reactions can be achieved in cancer cells, offering a new

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