I9783
Monoclonal Anti-Importin α3 antibody produced in rat
clone 3D10, purified immunoglobulin, buffered aqueous solution
别名:
Anti-Imp α
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所有图片(1)
About This Item
共軛:
unconjugated
application:
ARR
WB
WB
無性繁殖:
3D10, monoclonal
物種活性:
mouse, hamster, bovine, canine, rat, human, monkey
citations:
4
技術:
microarray: suitable
western blot: 2-4 μg/mL using HeLa cell extract
western blot: 2-4 μg/mL using HeLa cell extract
生物源
rat
品質等級
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
3D10, monoclonal
形狀
buffered aqueous solution
分子量
antigen ~60 kDa
物種活性
mouse, hamster, bovine, canine, rat, human, monkey
技術
microarray: suitable
western blot: 2-4 μg/mL using HeLa cell extract
同型
IgG2a
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... KPNA4(3840)
mouse ... Kpna4(16649)
rat ... Kpna4(361959)
免疫原
recombinant mouse importin α3/Qip1.
生化／生理作用
The gene KPNA4 (karyopherin subunit α 4) encodes a 16kDa protein, also referred to as importin α 3 belonging to the family of karyopherins (designated KPNA1 to KPNA4), that participates in the recognition of NLS (nuclear localization signal) sites and dock NLS-containing proteins destined for transport into the nuclear pore complex. It binds to translocon and participates in the sorting of INM (inner nuclear membrane)-directed integral membrane proteins. It associates with nucleoporins and functions in cargo-translocation across the nuclear membrane.
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
KPNA4 Mediates Vitamin D-Dependent Inhibition of NF-kB Activity in Swine Epicardial Preadipocytes.
Chen S
Circulation, A12818-A12818 (2014)
Sharon C Braunagel et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(22), 9307-9312 (2007-05-23)
Spodoptera frugiperda (Sf9) importin-alpha-16 is a translocon-associated protein that participates in the early sorting pathway of baculovirus integral membrane proteins destined for the inner nuclear membrane (INM). To discern whether sorting intermediate protein complexes like those observed in insect cells
Matthew Frieman et al.
Journal of virology, 81(18), 9812-9824 (2007-06-29)
The host innate immune response is an important deterrent of severe viral infection in humans and animals. Nuclear import factors function as key gatekeepers that regulate the transport of innate immune regulatory cargo to the nucleus of cells to activate
Annett Koch et al.
Cell cycle (Georgetown, Tex.), 10(8), 1200-1207 (2011-03-18)
It is well established that mutual relations exist between the oxidative status of a cell and the ubiquitin proteasome system (UPS). Oxidation of proteins leads to misfolding and thus claims a higher proteolytic activity of the UPS to dispose these
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