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描述
Ion Exchanger Type (value)
包裝
pack of 100 mL
製造商／商標名
Cytiva 17-5317-02
基質
highly cross-linked agarose
樣品平均尺寸
75 μm (d50v)
cleaning in place
2-14
工作範圍
2-12
容量
>45 mg binding capacity (BSA/ml medium at 30 mS/cm)
適合性
suitable for bioprocess medium
一般說明
Capto™ MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges.
Capto™ MMC is a multimodal cation exchanger, belonging to the Capto™ family of BioProcess media for fast, efficient and cost-effective protein purification. Capto™ MMC combines agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto™ MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges at both high and low ionic strengths.
The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto™ MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.
Capto™ MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto™ MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.
Capto™ MMC is a multimodal cation exchanger, belonging to the Capto™ family of BioProcess media for fast, efficient and cost-effective protein purification. Capto™ MMC combines agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto™ MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges at both high and low ionic strengths.
The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto™ MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.
Capto™ MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto™ MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.
Dynamic binding capacity at 10% breakthrough as measured at a residence time of 2 min, 300 cm/h in a Tricorn 5/100 column with 10-cm bed height in 50 mM Sodium acetate, pH 4.75, 250 mM NaCl.
特點和優勢
- Multimodal cation exchanger with a novel selectivity.
- High dynamic binding capacity at high conductivity increases productivity
- High-volume throughput cuts process times
- Smaller unit operations give cost-effective processing and reduce investments
儲存和穩定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
分析報告
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
法律資訊
Capto is a trademark of Cytiva
訊號詞
Warning
危險聲明
儲存類別代碼
3 - Flammable liquids
商品
Capto MMC is a multimodal cation exchanger with the properties of a weak cation exchanger. In addition to electrostatic interactions, the ligand structure provides for additional interaction modes such as hydrophobic interaction, hydrogen bonding, and thiophilic interaction.
This page describes the maintenance of media and storage conditions for multimodal chromatography using Cytiva products.
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