跳转至内容
Merck

G115080

Sigma-Aldrich

DMT-dG(dmf) Phosphoramidite

configured for PerkinElmer, configured for Polygen

别名:

DMT-dG(dmf) Amidite, N-[(二甲基氨基)亚甲基]-5′-O- [双(4-甲氧基苯基)苯基甲基]-2′-脱氧鸟苷,3′-[2-氰基乙基N,N-双(1-甲基乙基)亚磷酰胺], N2-二甲基甲脒基-5′-O-(4,4′-二甲氧基三苯甲基)-2′-脱氧鸟苷-3′-O-[O-(2-氰基乙基)-N,N′-二异丙基亚]

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C43H53N8O7P
分子量:
824.90
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.51

種類

for DNA synthesis

品質等級

產品線

Proligo Reagents

化驗

≥99% (31P-NMR)
≥99.0% (reversed phase HPLC)

形狀

powder

技術

oligo synthesis: suitable

顏色

white to off-white

&lambda ;

conforms (UV/VIS Identity)

相容性

configured for PerkinElmer
configured for Polygen

核苷譜

base: deoxyguanosine
base protecting group: DMF
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard

儲存溫度

-10 to -25°C

SMILES 字串

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(\N=C/N(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6

InChI

1S/C43H53N8O7P/c1-29(2)51(30(3)4)59(56-24-12-23-44)58-36-25-38(50-28-45-39-40(50)47-42(48-41(39)52)46-27-49(5)6)57-37(36)26-55-43(31-13-10-9-11-14-31,32-15-19-34(53-7)20-16-32)33-17-21-35(54-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H,47,48,52)/b46-27-/t36-,37+,38+,59?/m0/s1

InChI 密鑰

YRQAXTCBMPFGAN-UJASEYITSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides.Changing the dG protecting group to the dimethylformamide (dmf) base protecting group enables the rapid synthesis of high-purity, high-yieldoligonucleotide, thus increasing the efficiency of high-throughputproduction.Key Features of dG(dmf)
  • dG(dmf) is deprotected faster than the conventional dG(ib): thedeprotection time in concentrated ammonia is reduced to 2 hours at55 °C or 1 hour at 65 °C
  • The dG(dmf)-monomer is especially suitable for G-rich sequences:incomplete deprotection is greatly reduced in comparison with theconventional dG(ib)-monomer
  • dG(dmf)-phosphoramidite is as stable in solution as the standard dA(bz)-,dC(bz)- and dT-phosphoramidites
  • dG(dmf)-phosphoramidite can directly substitute for dG(ib)-phosphoramidite
  • No change is required in the reagents commonly used for DNA synthesis(except a low concentration iodine oxidizer i.e., 0.02 M in iodine, should beemployed)DMT-dG(dmf) Phosphoramidite is configured for Expedite and PolyGen® Synthesizers.

法律資訊

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries
PolyGen is a registered trademark of PolyGen GmbH.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门