E5156

盐酸依匹斯汀 盐酸盐

≥98% (HPLC), solid

• 别名: 9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride, WAL-801Cl
• 经验公式（希尔记法）: C₁₆H₁₅N₃ · HCl
• CAS号: 108929-04-0
• 分子量: 285.77
• MDL號碼: MFCD00933434
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24894608
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 顏色: white
• 溶解度: H₂O: 38 mg/mL
• 起源: Boehringer Ingelheim
• 儲存溫度: 2-8°C
• SMILES 字串: Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24
• InChI: 1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H
• InChI 密鑰: VKXSGUIOOQPGAF-UHFFFAOYSA-N
• 基因資訊: human ... HRH1(3269)

说明

一般說明

Epinastine has antihistamine functions. In mast cells, it may modulate cytokine and chemokine production. In dendritic cells, it controls T helper cell mediated immune response. Epinastine hydrochloride does not traverse the brain barrier. Oral dosage of epinastine hydrochloride is prescribed for children with sleep-disordered breathing (SDB) and nasal inflammation. Ophthalmic solution of epinastine is effective for allergic conjunctivitis.

生化／生理作用

Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.

特點和優勢

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges