跳转至内容
Merck

D4641

Sigma-Aldrich

十二烷基β-D-麦芽糖苷

≥98% (GC)

别名:

DDM, 月桂基-β-D-麦芽糖苷

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C24H46O11
CAS号:
分子量:
510.62
Beilstein:
55318
MDL號碼:
分類程式碼代碼:
12161900
eCl@ss:
32190102
PubChem物質ID:
NACRES:
NA.25

生物源

corn

描述

non-ionic

化驗

≥98% (GC)

形狀

powder

分子量

micellar avg mol wt 50,000

凝集数

98

技術

protein quantification: suitable

雜質

<1.5% water (Karl Fischer)

CMC

0.15 mM (20-25°C)

mp

224-226 °C (lit.)

溶解度

water: 50 mg/mL, clear to very slightly hazy, colorless

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI 密鑰

NLEBIOOXCVAHBD-QKMCSOCLSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

十二烷基-β-D-麦芽糖苷(N-dodecyl-β-D-maltoside)也称为月桂酰基麦芽糖苷,是一种非离子型表面活性剂和芘(Py)衍生物。作为烷基麦芽吡喃糖苷去污剂,对膜蛋白的溶解和结晶效用优异,是细胞生物学和生物化学研究的重要工具。它的独特性在于容易形成类似膜环境的胶束,从而维持膜结合蛋白的α-螺旋结构和天然构象。

十二烷基-β-D-麦芽糖苷还有其他多种用途,包括纯化和稳定RNA聚合酶、检测蛋白-脂质互作、作为糖原蛋白(glycogenin)催化葡萄糖基和木糖苷转移的底物。温和、非变性的特性适合蛋白-麻醉研究。总而言之,十二烷基-β-D-麦芽糖苷是一种多功能的去污剂,在膜蛋白等研究领域应用广泛。它维持蛋白结构和功能的重要特性令其成为膜生物学精细探索不可或缺的工具。

應用

正十二烷基β-D-麦芽糖甙已被用于一项研究,以评估通过GPS-NMR和散射技术映射整体螺旋膜蛋白的展开状态。
非离子型去污剂,用于酶的稳定和活化以及用于膜研究。

特點和優勢

  • 功能丰富的表面活性剂,适于细胞生物学和生物化学研究
  • 适于蛋白定量

其他說明

如需了解生化试剂系列的更多信息,请填写此表

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Kenneth P Watkins et al.
The Plant journal : for cell and molecular biology, 102(2), 369-382 (2019-12-04)
Synthesis of the D1 reaction center protein of Photosystem II is dynamically regulated in response to environmental and developmental cues. In chloroplasts, much of this regulation occurs at the post-transcriptional level, but the proteins responsible are largely unknown. To discover
Ka Young Chung et al.
The Journal of biological chemistry, 287(43), 36305-36311 (2012-08-16)
The G protein-coupled β(2)-adrenoreceptor (β(2)AR) signals through the heterotrimeric G proteins G(s) and G(i) and β-arrestin. As such, the energy landscape of β(2)AR-excited state conformers is expected to be complex. Upon tagging Cys-265 of β(2)AR with a trifluoromethyl probe, (19)F
Ryutaro Tokutsu et al.
The Journal of biological chemistry, 287(37), 31574-31581 (2012-07-18)
Photosystem II (PSII) is a multiprotein complex that splits water and initiates electron transfer in photosynthesis. The central part of PSII, the PSII core, is surrounded by light-harvesting complex II proteins (LHCIIs). In higher plants, two or three LHCII trimers
Antonello Calcutta et al.
Biochimica et biophysica acta, 1818(9), 2290-2301 (2012-04-25)
Membrane proteins are vital for biological function, and their action is governed by structural properties critically depending on their interactions with the membranes. This has motivated considerable interest in studies of membrane protein folding and unfolding. Here the structural changes
Signe Beck Petersen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 701-712 (2012-09-07)
Alkylmaltosides are a class of non-ionic surfactant currently in clinical trials to improve nasal permeation of peptide drugs, however few studies have detailed their potential effects on intestinal permeation enhancement. Tetradecyl maltoside (TDM, C(14)), was examined in Caco-2 monolayers and

实验方案

This page shows how to solubilize membrane proteins with products from Cytiva.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门