D2571

DPPE hydrochloride

≥98% (HPLC)

• 别名: BMS-217380-01, N,N-Diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine hydrochloride, Tesmilifene hydrochloride, YMB1002, [2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine hydrochloride
• 经验公式（希尔记法）: C₁₉H₂₅NO·HCl
• CAS号: 92981-78-7
• 分子量: 319.87
• MDL號碼: MFCD11114012
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329798745
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white
• 溶解度: H₂O: 16 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
• InChI: 1S/C19H25NO.ClH/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;/h5-13H,3-4,14-16H2,1-2H3;1H
• InChI 密鑰: TXLHNFOLHRXMAU-UHFFFAOYSA-N

说明

生化／生理作用

DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.

特點和優勢

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable