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product name
COV434, 07071909
生物源
human ovary
增長模式
Adherent
染色體組型
Modal chromosome no. 47 (46 - 47)
形態學
Polygonal & fusiform
產品
Not specified
受體
Not specified
技術
cell culture | mammalian: suitable
相關疾病
cancer
運輸包裝
dry ice
儲存溫度
−196°C
細胞系來源
Human ovarian granulosa tumour
細胞系描述
Human ovarian granulosa tumour cell line established from a solid primary tumour.
應用
COV434 has been used to study:
- the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
- if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
- the expression of TLR (toll-like receptor) and its function in the cell line
培養基
DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)
例行更新培養
Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm2 using trypsin/EDTA; 5% CO2; 37°C.
其他說明
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