所有图片(1)
About This Item
经验公式（希尔记法）:
C4H10N2O2 · HCl
CAS号:
分子量:
154.60
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32
推荐产品
品質等級
化驗
≥97% (NMR)
形狀
powder
光學活性
[α]/D +21 to +31°, c = 0.5 M in 0.1 M HCl(lit.)
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: soluble (solutions may be stored for several days at 4 °C)
儲存溫度
−20°C
SMILES 字串
Cl.CNC[C@H](N)C(O)=O
InChI
1S/C4H10N2O2.ClH/c1-6-2-3(5)4(7)8;/h3,6H,2,5H2,1H3,(H,7,8);1H/t3-;/m0./s1
InChI 密鑰
VDXYGASOGLSIDM-DFWYDOINSA-N
一般說明
L-BMAA 盐酸盐/ β-N-甲基氨基-1-丙氨酸（BMAA）是一种蓝藻神经毒素（cyanobacterial neurotoxin）。
應用
L-BMAA 盐酸盐可用作标准品，用于比较沙漠结皮（desert crust）材料的β-N-甲基氨基-1-丙氨酸（BMAA）异构体分析中的所有样品。它也已被用作f/2+Sii培养基的添加剂，用于处理三角藻（Phaeodyylum tricornutum）和威氏海链藻 （Thalassiosira weissflogii）细胞，以研究其对它们的作用。
生化／生理作用
L-BMAA盐酸盐有助于阻止硫酸乙酰肝素加入磷脂酰肌醇蛋白聚糖。它具有不同寻常的谷氨酸受体结合特性。它可引起肌萎缩性侧索硬化症/ Lou Gehrig′病。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Neurotoxic amino acids and their isomers in desert environments
Metcalf JS, et al.
Journal of arid environments, 140-144 (2015)
Olga A Koksharova et al.
Toxins, 12(6) (2020-06-10)
All cyanobacteria produce a neurotoxic non-protein amino acid β-N-methylamino-L-alanine (BMAA). However, the biological function of BMAA in the regulation of cyanobacteria metabolism still remains undetermined. It is known that BMAA suppresses the formation of heterocysts in diazotrophic cyanobacteria under nitrogen
David A Davis et al.
Journal of neuropathology and experimental neurology, 79(4), 393-406 (2020-02-23)
The early neuropathological features of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) are protein aggregates in motor neurons and microglial activation. Similar pathology characterizes Guamanian ALS/Parkinsonism dementia complex, which may be triggered by the cyanotoxin β-N-methylamino-l-alanine (BMAA). We report here the
The cyanobacterial neurotoxin beta-N-methylamino-l-alanine prevents addition of heparan sulfate to glypican-1 and increases processing of amyloid precursor protein in dividing neuronal cells
Cheng F, et al.
Experimental Cell Research (2019)
Aifeng Li et al.
Aquatic toxicology (Amsterdam, Netherlands), 221, 105425-105425 (2020-02-15)
Neurotoxin β-N-methylamino-L-alanine (BMAA) has been widely detected in diverse aquatic organisms and hypothesized as an environmental risk to neurodegenerative diseases in humans. However, the knowledge of its toxicity to marine organisms requires attention. In the present study, embryos and sperm
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门