AV31592

Anti-AEBP1 antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-AE binding protein 1
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 131 kDa
• 物種活性: rabbit, horse, guinea pig, rat, human
• 濃度: 0.5 mg - 1 mg/mL
• 技術: immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_001120
• UniProt登錄號: Q8IUX7
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... AEBP1(165)

说明

一般說明

AEBP1 is a transcriptional repressor that negatively regulates PTEN. This transcription factor is involved in adipocyte growth and is a sex-specific risk factor for diet-induced obesity. Furthermore, AEBP1 is also known to have proinflammatory roles in macrophages.
Rabbit Anti-AEBP1 antibody recognizes human, mouse, rat, and pig AEBP1.

The previously assigned protein identifier Q14113 has been merged into Q8IUX7. Full details can be found on the UniProt database.

免疫原

Synthetic peptide directed towards the N terminal region of human AEBP1

應用

Rabbit Anti-AEBP1 antibody can be used for immunohistochemical assays at concentration of 4-8μg/ml. It can also be used for western blot (0.2-5.0μg/ml) applications.

生化／生理作用

The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.

序列

Synthetic peptide located within the following region: VPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEK

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable