跳转至内容
Merck
所有图片(3)

Key Documents

View All Documentation

A6779

Sigma-Aldrich

高碘酸氧化腺苷 5′-三磷酸 钠盐

≥97%

别名:

oATP, 腺苷 5′-三磷酸-2′,3′-二醛

登录查看公司和协议定价
所有图片(3)

About This Item

经验公式（希尔记法）:
C10H14N5O13P3
CAS号:
71997-40-5
分子量:
505.17
MDL號碼:
MFCD00056956
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
24891137
NACRES:
NA.51

生物源

bacterial (corynebacterium sp)

化驗

≥97%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O

InChI

1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1

InChI 密鑰

IHQATUPGVKMGLT-AUCRBCQYSA-N

相关类别

一般說明

腺苷-5′-三磷酸-2′，3′-二醛是二醛的一种衍生物。

應用

腺苷-5′-三磷酸，高碘酸氧化钠盐已被用于：
  • 作为嘌呤能受体的拮抗剂（P2×7抑制P2×7通路）
  • 作为通过Ca2+评估P2x7-R活性的非特异性激动剂
  • 评估细胞内ATP水平升高的生理意义
  • 评估Flcn缺陷细胞中用于破骨细胞生成的P2rx7表达升高的生理意义

生化／生理作用

腺苷-5′-三磷酸-2′，3′-二醛被认为是P2×7受体的一种抑制剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells
Derangere V, et al.
Cell Death and Differentiation, 21(12), 1914-1914 (2014)
Searching Novel Therapeutic Targets for Scleroderma: P2X7-Receptor Is Up-regulated and Promotes a Fibrogenic Phenotype in Systemic Sclerosis Fibroblasts.
Daniela Gentile et al.
Frontiers in pharmacology, 8, 638-638 (2017-09-29)
Xuejing Cui et al.
Small (Weinheim an der Bergstrasse, Germany), 12(43), 5998-6011 (2016-09-21)
Exocytosis of single-walled carbon nanotubes (SWCNTs) determines therapeutic efficiency and toxicity of nanoproducts but its underlying mechanism remains elusive. In this study, it is found that the exocytosis mechanism of SWCNTs is mediated mainly through the activation of P2X7 receptor
Ursula Schenk et al.
Science signaling, 1(39), ra6-ra6 (2008-10-02)
T cell receptor (TCR) stimulation results in the influx of Ca(2+), which is buffered by mitochondria and promotes adenosine triphosphate (ATP) synthesis. We found that ATP released from activated T cells through pannexin-1 hemichannels activated purinergic P2X receptors (P2XRs) to
William Foulsham et al.
Scientific reports, 9(1), 8617-8617 (2019-06-15)
Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory mechanisms of the purinergic receptor
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门