![N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸](/deepweb/assets/sigmaaldrich/product/structures/225/349/530bc714-b1a8-4fdb-8082-a39329ee730a/640/530bc714-b1a8-4fdb-8082-a39329ee730a.png)
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
价格与库存信息目前不能提供
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一般說明
應用
生化／生理作用
去除易受影响的底物（如紧张素 I 和缓激肽）中的 C-端二肽。
品質
可能含微量氯化钠。
單位定義
在pH为8.3，温度为37°C的条件下，在50mM HEPES和300mM NaCl中，一个单位每分钟可将1.0μmole的马尿酰组氨酰亮氨酸转化成马尿酸。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Angiotensin-converting enzyme inhibitory activity of milk protein hydrolysates: Effect of substrate, enzyme and time of hydrolysis
Otte J, et al.
International dairy journal, 17(5), 488-503 (2007)
M Hernández-Presa et al.
Circulation, 95(6), 1532-1541 (1997-03-18)
The migration of monocytes into the vessel wall is a critical event leading to the development of atherosclerosis. Monocyte chemoattractant protein-1 (MCP-1) is the main chemotactic factor involved in this phenomenon, and nuclear factor-kappa B (NF-kappa B) is one of
Mina Ojaghi et al.
Molecular reproduction and development, 84(5), 376-388 (2017-03-01)
We hypothesized that the testis-specific isoform of angiotensin-converting enzyme (tACE) is released during bovine sperm capacitation, and its peptidase activity is required for capacitation. Specific objectives of this study were to (i) develop an anti-tACE antibody; (ii) characterize expression of
Yating Lu et al.
Journal of Zhejiang University. Science. B, 22(7), 575-589 (2021-07-17)
The aim of this work is to discover the inhibitory mechanism of tea peptides and to analyse the affinities between the peptides and the angiotensin-converting enzyme (ACE) as well as the stability of the complexes using in vitro and in
Angiotensin converting enzyme (ACE) inhibitory peptides derived from the simulated in vitro gastrointestinal digestion of cooked chicken breast
Sangsawad P, et al.
Journal of functional foods, 29, 77-83 (2017)
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What is the Department of Transportation shipping information for this product?
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What is the effect of bleomycin on Angiotensin Converting Enzyme (ACE) activity in vivo?
1 answer-
Bleomycin causes a marked reduction in rabbit lung ACE activity. Reference: Cancer Research, 40, 3621-3626, (1980).
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Are there any other known inhibitors of rabbit lung Angiotensin Converting Enzyme (ACE), Product A6778?
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Idrapril, the prototype of a new class of angiotensin converting enzyme (ACE) inhibitors, competitively inhibits, with nanomolar apparent Ki, the hydrolysis of hippuryl-glycyl-glycine by rabbit lung ACE. Kinetic Ki and kon and koff values were 470 pM, 3.0±1.5×106 M-1sec-1 and 1.4±0.3×10-3 sec-1, respectively. Reference: Biochemical Pharmacology, 45(6), 1358-1362 (1993).
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What is the medical significance of Angiotensin Converting Enzyme (ACE), Product A6778?
1 answer-
Angiotensin-converting enzyme (ACE) produces angiotensin II, a substance that affects the cardiovascular system in numerous ways, including narrowing of blood vessels. This narrowing can cause high blood pressure and cause the heart to work harder. ACE inhibitors treat a variety of conditions, such as high blood pressure, scleroderma and migraines. (Mayo Clinic)
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