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应用
D-氨基酸氧化酶（DAO）是治疗慢性疼痛和精神分裂症的潜在靶分子。 D-氨基酸氧化酶可用于将D-氨基酸氧化成其相应的亚氨基酸。
单位定义
在过氧化氢酶存在下，一单位酶在pH 8.3、25℃条件下每分钟可使1.0 μmM D-丙氨酸氧化脱氨成丙酮酸。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Cindy J Lee et al.
Metabolites, 12(9) (2022-09-24)
The pancreatic islets of Langerhans are clusters of cells that function as endocrine units synthesizing and releasing insulin and a range of additional peptide hormones. The structural and chemical characteristics of islets change during type 2 diabetes development. Although a
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP.
Andrea V Canosa et al.
Scientific reports, 8(1), 9016-9016 (2018-06-15)
Serine racemase (SR) catalyses two reactions: the reversible racemisation of L-serine and the irreversible dehydration of L- and D-serine to pyruvate and ammonia. SRs are evolutionarily related to serine dehydratases (SDH) and degradative threonine deaminases (TdcB). Most SRs and TdcBs
Pamela Cappelletti et al.
The FEBS journal, 281(3), 708-723 (2013-11-19)
Human D-amino acid oxidase (EC 1.4.3.3; hDAAO) is a peroxisomal flavoenzyme significantly enriched in the mammalian brain. hDAAO has been proposed to play (with serine racemase; EC 5.1.1.18) an essential role in the catabolism of D-serine, an 'atypical' key signalling
Masumi Katane et al.
Journal of medicinal chemistry, 56(5), 1894-1907 (2013-02-09)
D-amino acid oxidase (DAO) is a degradative enzyme that is stereospecific for D-amino acids, including D-serine and D-alanine, which are potential coagonists of the N-methyl-D-aspartate (NMDA) receptor. Dysfunction of NMDA receptor-mediated neurotransmission has been implicated in the onset of various
Chi-Hua Nieh et al.
Biosensors & bioelectronics, 47, 350-355 (2013-04-23)
A sensitive d-amino acid oxidase (DAAO)/peroxidase (POD) bienzyme biosensor is constructed, in which pentacyanoferrate-bound poly(1-vinylimidazole) polymer (PVI[Fe(CN)5]) is selected as a mediator. Reductive current of PVI[Fe(CN)5] related to the H2O2 concentration generated in the DAAO reaction was measured at -0.1V
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