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Merck
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文件

72779

Sigma-Aldrich

三氯生

97.0-103.0% (active substance, GC)

别名:

三氯苯氧氯酚, 5-氯-2-（2,4-二氯苯氧基）苯酚, 氯苯酚

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About This Item

经验公式（希尔记法）:
C12H7Cl3O2
CAS号:
3380-34-5
分子量:
289.54
Beilstein:
2057142
EC號碼:
222-182-2
MDL號碼:
MFCD00800992
分類程式碼代碼:
12352132
PubChem物質ID:
57652433
NACRES:
NA.85

生物源

synthetic

化驗

97.0-103.0% (active substance, GC)

形狀

powder or crystals

雜質

≤0.1% Water (Karl Fischer)

顏色

white

mp

55-59 °C

溶解度

1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)

抗生素活性譜

fungi

作用方式

enzyme | inhibits

SMILES 字串

Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl

InChI

1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

InChI 密鑰

XEFQLINVKFYRCS-UHFFFAOYSA-N

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相关类别

一般說明

化学结构式：二苯醚衍生物

應用

一种可能污染动物性食品的人类病原体—耶尔森氏菌的头孢菌素-伊桑-新生物素选择培养基的组成部分。

生化／生理作用

它是细菌和疟原虫II型脂肪酸合成酶(FAS-II)的烯酰ACP（酰基载体蛋白）还原酶组分的抑制剂。 它还能抑制哺乳动物脂肪酸合成酶（FASN），可能具有抗癌活性。

其他說明

将容器紧紧地封闭在干燥通风良好的地方。保存在干燥的地方。

象形圖

Exclamation markEnvironment
GHS07,GHS09

訊號詞

Warning

危險聲明

H315,H319,H410

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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Kathleen Dittmann et al.
Antimicrobial resistance and infection control, 8, 122-122 (2019-08-02)
Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA), hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA) to the commonly used
Markus K Diener et al.
Lancet (London, England), 384(9938), 142-152 (2014-04-11)
Postoperative surgical site infections are one of the most frequent complications after open abdominal surgery, and triclosan-coated sutures were developed to reduce their occurrence. The aim of the PROUD trial was to obtain reliable data for the effectiveness of triclosan-coated
Siamak P Yazdankhah et al.
Microbial drug resistance (Larchmont, N.Y.), 12(2), 83-90 (2006-08-23)
Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different microorganisms. It is included in many contemporary consumer and personal health-care products, like oral and dermal products, but also in household items, including plastics
R M Davies et al.
Journal of clinical periodontology, 31(12), 1029-1033 (2004-11-25)
To compare the effectiveness of triclosan/copolymer and fluoride dentifrices in improving plaque control and gingival health. We searched the Cochrane Controlled Trials Register, MEDLINE (1986 to March 2003) and EMBASE (1986 to March 2003). Personal files and the reference lists
Wai Keat Chang et al.
Annals of surgery, 255(5), 854-859 (2012-04-04)
To determine the efficacy and safety of triclosan-impregnated sutures. Surgical-site infections (SSIs) produce considerable morbidity and increase health care costs. A potential strategy to decrease the rates of SSIs may be the use of triclosan-impregnated sutures. These have been endorsed
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