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Merck

56759

Sigma-Aldrich

Atto 425

BioReagent, suitable for fluorescence

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About This Item

经验公式(希尔记法):
C22H27NO6
分子量:
401.45
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32

產品線

BioReagent

品質等級

化驗

≥90% (HPLC)

形狀

(Report result)

製造商/商標名

ATTO-TEC GmbH

透射率

254 nm, >90%
425 nm, >90%

螢光

λex 440 nm; λem 484 nm

&lambda ;

in PBS, pH 7.4
in ethanol (with 0.1% trifluoroacetic acid)

紫外吸收

λ: 423-429 nm Amax

適合性

suitable for fluorescence

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

CCOC(=O)C1=Cc2cc3C(C)CC(C)(C)N(CCCC(O)=O)c3cc2OC1=O

InChI

1S/C22H27NO6/c1-5-28-20(26)16-10-14-9-15-13(2)12-22(3,4)23(8-6-7-19(24)25)17(15)11-18(14)29-21(16)27/h9-11,13H,5-8,12H2,1-4H3,(H,24,25)

InChI 密鑰

WNDDWSAHNYBXKY-UHFFFAOYSA-N

應用

Atto 荧光标记专门设计用于高灵敏度应用,包括单分子检测。Atto 标记具有刚性结构,不显示任何顺反异构化。因此,这些标记物在偶联时显示出极低的光谱偏移和异常的强度。Atto 425 适合于制备荧光标记试剂。

法律資訊

本产品仅供研究使用。如果打算商业化,请联系知识产权持有者(德国ATTO-TEC GmbH公司)申请许可。

儲存類別代碼

11 - Combustible Solids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anna I Sulatskaya et al.
The journal of physical chemistry. B, 115(39), 11519-11524 (2011-08-26)
The fluorescence of the benzothiazole dye thioflavin T (ThT) is a well-known test for amyloid fibril formation. It has now become evident that ThT can also be used for structural investigations of amyloid fibrils and even for the treatment of
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Journal of the American Chemical Society, 132(17), 6075-6080 (2010-04-13)
A fluorescent sensor of protein kinase activity has been developed and used to characterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria. The sensor functions via a phosphorylation-induced release of a quencher from a peptide-based substrate, producing a
Anna I Sulatskaya et al.
The journal of physical chemistry. B, 116(8), 2538-2544 (2012-01-25)
Benzothiazole dye thioflavin T (ThT) is a sensitive probe for amyloid fibril detection. The ThT probing is based on its unique ability to form highly fluorescent complexes with amyloid and amyloid-like fibrils. In this work we propose an approach of

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