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产品名称
Nα-Methyl-L-ornithine monohydrochloride, ≥98% (TLC)
质量水平
方案
≥98% (TLC)
表单
powder
旋光性
[α]/D +27.0±1.0°, c = 1 in 1 M HCl
组成
carbon, 38.7-40.2%
nitrogen, 14.9-15.7%
SMILES字符串
Cl.CN[C@@H](CCCN)C(O)=O
InChI
1S/C6H14N2O2.ClH/c1-8-5(6(9)10)3-2-4-7;/h5,8H,2-4,7H2,1H3,(H,9,10);1H/t5-;/m0./s1
InChI key
OUPNMQRLBAANLP-JEDNCBNOSA-N
生化/生理作用
Nα-Methyl-L-ornithine has been identified as an inhibitor of nitric oxidase synthase in macrophages.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
T B McCall et al.
British journal of pharmacology, 102(1), 234-238 (1991-01-01)
1. The synthesis of nitric oxide (NO) from L-arginine by rat peritoneal neutrophils (PMN) and the murine macrophage cell-line J774 and the inhibition of this synthesis by N-iminoethyl-L-ornithine (L-NIO), NG-monomethyl-L-arginine (L-NMMA), NG-nitro-L-arginine (L-NNA) and its methyl ester (L-NAME) were investigated.
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta
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