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Merck

18726

Sigma-Aldrich

Nα-Methyl-L-ornithine monohydrochloride

≥98% (TLC), powder

别名:

(S)-5-Amino-2-(methylamino)pentanoic acid hydrochloride, N-Me-Orn-OH · HCl

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About This Item

经验公式(希尔记法):
C6H14N2O2 · HCl
CAS号:
分子量:
182.65
Beilstein:
6117952
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.32

产品名称

Nα-Methyl-L-ornithine monohydrochloride, ≥98% (TLC)

质量水平

方案

≥98% (TLC)

表单

powder

旋光性

[α]/D +27.0±1.0°, c = 1 in 1 M HCl

组成

carbon, 38.7-40.2%
nitrogen, 14.9-15.7%

SMILES字符串

Cl.CN[C@@H](CCCN)C(O)=O

InChI

1S/C6H14N2O2.ClH/c1-8-5(6(9)10)3-2-4-7;/h5,8H,2-4,7H2,1H3,(H,9,10);1H/t5-;/m0./s1

InChI key

OUPNMQRLBAANLP-JEDNCBNOSA-N

生化/生理作用

Nα-Methyl-L-ornithine has been identified as an inhibitor of nitric oxidase synthase in macrophages.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T B McCall et al.
British journal of pharmacology, 102(1), 234-238 (1991-01-01)
1. The synthesis of nitric oxide (NO) from L-arginine by rat peritoneal neutrophils (PMN) and the murine macrophage cell-line J774 and the inhibition of this synthesis by N-iminoethyl-L-ornithine (L-NIO), NG-monomethyl-L-arginine (L-NMMA), NG-nitro-L-arginine (L-NNA) and its methyl ester (L-NAME) were investigated.
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta

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